Paraxial mesoderm as a direct gateway to lymphatic endothelial cells

januari 16, 2025

Valeria Orlova and Tatiana Petrova have published a paper in Nature Cardiovascular Research in which the origins of mammalian lymphatic vessels have been studied. In conclusion, the centripetal model via the paraxial mesoderm lineage may offer a more promising approach for direct differentiation of LECS in vitro without the need to pass through an intermediate venous lineage via the centrifugal model.

The link to the full publication is: https://rdcu.be/d5ovE

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LymphChip review paper on the interplay between lymph node extracellular matrix, fibroblasts and immune cells

maart 7, 2025

Daphne Panocha and Reina Mebius have published a review in Trends in Immunology about the complex interplay between lymph node extracellular matrix, fibroblasts and immune cells. Understanding this interplay will help the development of a human physiological lymph node-on-chip which can mimic human adaptive immune responses. The link to the full publication is: Lymph node fibroblast-produced […]

Successful Workshop on Maskless Photolithography & Nano-Indentation

maart 4, 2025

On March 4th, the LUMC OoC Centre, Alvéole and Optics11 Life together organized a workshop focused on maskless photolithography and nano-indentation techniques. The day started with an introduction to the techniques and how to apply them to a range of research questions by experts from both companies and the LUMC. Following the introduction, the participants […]

LymphChip cardiac microtissue paper among the top 10 cited papers in Stem Cell Reports

februari 27, 2025

Stem Cell Reports has presented a list of the 10 highly cited publications published during 2023-2024. The publication of Ulgu Arslan on vascularized hiPSC-derived 3D cardiac microtissue on chip is one of these papers, please see the link below. Top-cited stem cell papers We are pleased to present a selection of highly cited papers published […]