Kick-off Immuno-Gut (spin-off LymphChip Helpathon)

maart 30, 2024

The kick-off meeting of Immuno-Gut took place on March 28, 2024 at the Mirai House home of the Department of Anatomy and Embryology of LUMC.

This project is financed with a phase 1 Create2Solve grant from ZonMw and aims at the optimization and standardization of methods to produce serum and Matrigel free iPSC derived immune competent intestine via an intra- and inter-laboratory validation study. Sue Gibbs from Amsterdam UMC, location VUMc coordinates this project in a collaboration with LUMC and NCardia.

The foundation for this project was laid during the LymphChip Helpathon #8 on finding animal-free alternatives for fetal calf serum and Matrigel that was held in May 2023 in Amsterdam.

During this kick-off Initial results were shared and action points were discussed.

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Paraxial mesoderm as a direct gateway to lymphatic endothelial cells

januari 16, 2025

Valeria Orlova and Tatiana Petrova have published a paper in Nature Cardiovascular Research in which the origins of mammalian lymphatic vessels have been studied. In conclusion, the centripetal model via the paraxial mesoderm lineage may offer a more promising approach for direct differentiation of LECS in vitro without the need to pass through an intermediate […]

Workshop Maskless Photolitography & Indentation

Workshop: Maskless Photolithography & Indentation

januari 28, 2025

Dear LymphChip members, On March 4 the hands-on Workshop: Maskless Photolithography & Indentation organized by Alvéole, Optics11 Life and LUMC will be held at Sylviusweg 62 in Leiden, The Netherlands. A QR code to register for this workshop is presented in the attached flyer and below. Costs are 200 Euro (academic), 230 Euro (industry).

Midterm Self-evaluation LymphChip

november 25, 2024

Three NWA-ORC consortia: BioClock, LOSS and LymphChip met November 25 at the Lorentz Center in Leiden for a midterm self-evaluation to work towards societal impact. During the day best practices, challenges, needs and actions were discussed by young and senior researchers and by representatives from co-funding and cooperation partners.