Auteur: LymphChip

Dear LymphChip members, On January 21 the hands-on Workshop: Maskless Photolithography & Indentation organized by Alvéole, Optics11 Life and LUMC will be held at Sylviusweg 62 in Leiden, The Netherlands. A QR code to register for this workshop is presented in the attached flyer and below. Costs are 200 Euro (academic), 230 Euro (industry). Download the flyer

Three NWA-ORC consortia: BioClock, LOSS and LymphChip met November 25 at the Lorentz Center in Leiden for a midterm self-evaluation to work towards societal impact. During the day best practices, challenges, needs and actions were discussed by young and senior researchers and by representatives from co-funding and cooperation partners.

On November 22, Hans Bouwmeester, PI in LymphChip presented his inaugural lecture entitled: “Is complexity always better? Connecting cells to systems in toxicology”. Within LymphChip, Hans Bouwmeester takes the lead in the development of an immunocompetent Intestine-on-chip model.

Early-career researchers: Please sign up for the Young TPI Impact Workshop on October 31st in Utrecht. A few in-person spots are still available. Sign up now and don’t miss out: https://lnkd.in/eQJP42KA In this hands-on workshop, we’ll dive into topics such as overcoming animal bias in publishing, transforming research into products and services, and communicating your findings to any audience. Bonus: Pitch Training & Toekomstproef Event You’ll also get professional pitch training and the chance to present your research to a live audience at Proefdiervrij’s Toekomstproef...

On October 21-22, the third Annual Meeting of LymphChip took place at the Leiden University Medical Center (LUMC), bringing together 35 participants from our academic and co-financing partners, as well as members of the Advisory Board. The event kicked off with research updates from all work packages, providing a comprehensive overview of the progress made across various projects. The evening concluded with an engaging dinner, where most attendees gathered to continue discussions in a more informal setting. On the second day, we introduced a new breakout session format to explore collaboration...

Theano Tsikari, PhD student within LymphChip at the Orlova lab at LUMC, has been selected to give a flash talk and has also received a travel grant for the EMBO workshop entitled “Building networks: engineering in vascular biology” which is held in Barcelona on May 6-8, 2024. In addition, she has been invited to give a short talk at the Annual EUROoCS meeting that will take place on July 3-5 in Milan. On both occasions, Theano will present her results on the integration of hiPSC-derived macrophages in a 3D vessel-on-chip model.

Researchers of both LymphChip and SmartOoC academic partners are invited to attend the LymphChip Summer School 2024 which will feature workshops on career development, business development, academic writing and scientific illustrations. The deadline for registration is May 1, 2024. For more information, please contact Anne Leferink.

The kick-off meeting of Immuno-Gut took place on March 28, 2024 at the Mirai House home of the Department of Anatomy and Embryology of LUMC. This project is financed with a phase 1 Create2Solve grant from ZonMw and aims at the optimization and standardization of methods to produce serum and Matrigel free iPSC derived immune competent intestine via an intra- and inter-laboratory validation study. Sue Gibbs from Amsterdam UMC, location VUMc coordinates this project in a collaboration with LUMC and NCardia. The foundation for this project was laid during the LymphChip Helpathon #8 on finding...

Hans van der Aa, COO of PolyVation, gave a technology seminar in which he presented the capabilities of PolyVation and the various applications of their custom-made polymers. Depending on the need of the customer, the properties of the polymers can be tweaked to control for instance the physical and biological properties of the materials. Application areas of these polymers include medical devices, tissue engineering and drug delivery.  Within LymphChip, the PolyVation polymers are used for the biofabrication of biomimetic 3D microscaffolds for advanced skin‑ and gut-on-chip models with integrated...

This year Massimo Mastrangeli was appointed as Associate Professor at TU Delft. In his research he exploits his knowledge on microelectronics to create a home for human cells outside the human body. With a combination of soft and hard materials an environment is created to host cells or tissues, the chip. Stimulation of these cells or tissues with electricity, motion, mechanical power and chemicals allow them to grow and mature and function as a mini organ. Moreover, the chips are equipped to record signals to monitor the cells and tissues. To be able to see what is happening inside the chip...

On October 30-31 the second Annual Meeting of LymphChp was hosted by VUMC in Amsterdam. In total 39 members of LymphChip attended the program representing the academic partners, co-financing partners and the Advisory Board. The first day consisted of news updates on behalf of all the work packages. Most attendees joined for dinner that evening. On the second day invited lectures were given by representatives from industry and the Advisory Board followed by break-out sessions on topics selected on the spot and relating to technological and biological challenges. The newly designed chip,...