Kick-off Immuno-Gut (spin-off LymphChip Helpathon)

maart 30, 2024

The kick-off meeting of Immuno-Gut took place on March 28, 2024 at the Mirai House home of the Department of Anatomy and Embryology of LUMC.

This project is financed with a phase 1 Create2Solve grant from ZonMw and aims at the optimization and standardization of methods to produce serum and Matrigel free iPSC derived immune competent intestine via an intra- and inter-laboratory validation study. Sue Gibbs from Amsterdam UMC, location VUMc coordinates this project in a collaboration with LUMC and NCardia.

The foundation for this project was laid during the LymphChip Helpathon #8 on finding animal-free alternatives for fetal calf serum and Matrigel that was held in May 2023 in Amsterdam.

During this kick-off Initial results were shared and action points were discussed.

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Application Note Fluigent

januari 27, 2026

Flow conditions and a stable well-defined flow direction are important to culture in vivo-like endothelial cells over time that maintain their organization and function. With help of Dhanesh Khasi, Hanna Lammertse and Valeria Orlova, an application note was put together by Fluigent describing the proper conditions for hiPSCs-derived vascular organ-on-chip model under unidirectional controlled flow: https://www.fluigent.com/resources-support/expertise/application-notes/hipscs-derived-vascular-organ-on-chip

Strategic Workshops Catalyze

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As part of our aim to identify opportunities for valorization, Catalyze gave two Strategic Workshops on January 20. The first workshop was aimed at LymphChip PIs and their senior colleagues and concentrated on the first steps to translate a (scientific) innovation/tool into a marketable product. In the second workshop options for future funding for LymphChip […]

januari 16, 2026

Peerlogic is a tool to facilitate animal-free cell culturing. To this end protocols and Materials & Methods sections for xeno-free & FCS-free cell culturing are being shared as well as animal-free alternatives to basement membrane extracts (BME) such as Matrigel. With this tool we want to stimulate collaboration and through peer review we want to […]