
Paraxial mesoderm as a direct gateway to lymphatic endothelial cells
January 16, 2025
Valeria Orlova and Tatiana Petrova have published a paper in Nature Cardiovascular Research in which the origins of mammalian lymphatic vessels have been studied. In conclusion, the centripetal model via the paraxial mesoderm lineage may offer a more promising approach for direct differentiation of LECS in vitro without the need to pass through an intermediate venous lineage via the centrifugal model.
The link to the full publication is: https://rdcu.be/d5ovE
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Technology Seminar: ibidi–Cells in Focus
March 25, 2025
Christiane Thanisch from ibidi presented the latest products designed to facilitate cell-based assays and imaging. She highlighted the imaging properties of the ibidi polymer and presented culture systems that allow the application of flow. She also focused on migration/invasion assays and various 3D applications. To support researchers, a wide range of downloadable material is available, […]

LymphChip review paper on the interplay between lymph node extracellular matrix, fibroblasts and immune cells
March 7, 2025
Daphne Panocha and Reina Mebius have published a review in Trends in Immunology about the complex interplay between lymph node extracellular matrix, fibroblasts and immune cells. Understanding this interplay will help the development of a human physiological lymph node-on-chip which can mimic human adaptive immune responses. The link to the full publication is: Lymph node […]

Successful Workshop on Maskless Photolithography & Nano-Indentation
March 4, 2025
On March 4th, the LUMC OoC Centre, Alvéole and Optics11 Life together organized a workshop focused on maskless photolithography and nano-indentation techniques. The day started with an introduction to the techniques and how to apply them to a range of research questions by experts from both companies and the LUMC. Following the introduction, the participants […]