Create2Solve grant

December 6, 2023

In May 2023, LymphChip organized Helpathon #8 asking help to find animal-free alternatives for serum and Matrigel. As a direct result of this Helpathon, an application was submitted to the Create2Solve Phase 1 call of ZonMw to optimize and standardize methods to produce serum and Matrigel free iPSC derived immune competent intestine: Immuno-Gut.

Immuno-Gut got granted and the aim is to develop methods and carry out an and inter-laboratory validation study to obtain robust data for animal free production of immune competent iPSC derived intestine organoids. In Phase 1 products will be tested which do not contain Matrigel and FCS. The most promising, and where possible, totally xeno-free products will be selected for further validation in an inter-laboratory study in Phase 2.

Sue Gibbs and Valeria Orlova with help from BioTechne, Miltenyi, Stem Cell Technologies, three companies that participated in the Helpathon as well as NCardia will work together in Phase 1.

For more information see: https://www.zonmw.nl/en/news/6-project-groups-take-challenges-develop-animal-free-innovations

More news

Workshop: Maskless Photolithography & Indentation

December 9, 2024

Dear LymphChip members, On January 21 the hands-on Workshop: Maskless Photolithography & Indentation organized by Alvéole, Optics11 Life and LUMC will be held at Sylviusweg 62 in Leiden, The Netherlands. A QR code to register for this workshop is presented in the attached flyer and below. Costs are 200 Euro (academic), 230 Euro (industry).

Midterm Self-evaluation LymphChip

November 25, 2024

Three NWA-ORC consortia: BioClock, LOSS and LymphChip met November 25 at the Lorentz Center in Leiden for a midterm self-evaluation to work towards societal impact. During the day best practices, challenges, needs and actions were discussed by young and senior researchers and by representatives from co-funding and cooperation partners.

Inaugural lecture Hans Bouwmeester LymphChip

November 22, 2024

On November 22, Hans Bouwmeester, PI in LymphChip presented his inaugural lecture entitled: “Is complexity always better? Connecting cells to systems in toxicology”. Within LymphChip, Hans Bouwmeester takes the lead in the development of an immunocompetent Intestine-on-chip model.