Author: LymphChip

On November 12, 2021 Dr Valeria Orlova the project leader of LymphChip will present the LympChip consortium to the members of hDMT. She will highlight the objectives of the three research themes on technology development, on the generation of the hiPSC-derived tissue specific cells and on the integration to ultimately lead to functional organs on chip with integrated vasculature and lymphatics for heart, intestine and skin/lymph nodes.

On October 25, 2021 the principal investigators of LymphChip gathered online to discuss amongst others the recruitment of PhD students and postdocs (we do have vacancies, please keep an eye on the vacancies page on our website) and the kick-off meeting that is scheduled for February 15, 2022.

A 5 million Euro NWA-ORC grant was awarded to hDMT researchers to develop immunocompetent human Organ-on-Chip models with integrated lymph drainage for drug discovery and testing (LymphChip). The project is led by Valeria Orlova (coordinator) from Leiden University Medical Center (LUMC), Christine Mummery (LUMC) and Sue Gibbs (VUMC). The lymphatic system plays a crucial role in our immune system, for example by regulating the immune response to pathogens. Lymphatic dysfunction underlies many diseases and could determine the effectiveness of therapies, whether drug or stem-cell based. Yet,...